RTS-1 used to cultivate L. plantarum in study - Response of Lactobacillus sp. in different physiological state to the oxidative stress induced by H2O2 and ionizing radiation

Ionizing radiation exposure leads to oxidative damages in organisms. Free radicals produced by oncology radiotherapy are often a source of serious side effects. Resistance of lactobacilli to oxidative stress is of great importance for their applicability as probiotics. This response is strongly dependent on the type of cell metabolism.
In contrast to heat, acid and detergent stresses, which respond to growth phase and adaptation, tolerance to oxidative stress implies completely unrelated mechanisms (Ricciardi et al., 2012).
Thus, on the one hand, a high resistance of lactobacilli to gamma irradiation is proved, on the other hand, serious disorders in the microbial (probably, also lactobacilli) ecosystem in the human organism are caused by ionizing radiation.