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Cell Biology

  • PANSys 3000
PANSys 3000
PANsys3000 ist ein hoch automatisiertes Zellkultursystem, das eine signifikante Reduktion der manuellen Prozesse sowie eine vollständige Kontrolle und Dokumentation aller Zellkultur-Parameter erlaubt. Neben der automatisiert durchgeführten Steuerung und Kontrolle der wichtigsten Zellkulturparameter bietet das System eine integrierte und automatisierte Auswertung der Zellen (Wachstum, Stoffwechsel, Morphologie).

Die speziell entwickelte Kammer ist das Kernstück der Zellkultureinheit. In den Zellkulturkammern werden die Zellen unter den gewählten Kulturparametern mit den entsprechenden Nährmedien automatisch versorgt.

Die präzise steuerbare und fahrbare Optik ist mit einem hochauflösenden CCD-Mikroskop (Durchlicht, Phasenkontrast und Fluoreszenz) ausgerüstet. Sie nimmt nach entsprechender Zeitvorgabe Bilder von jedem frei wählbaren Punkt (Point-of-Interest, POI) der Zellkultur auf, die von der Software gespeichert und am PC online ausgewertet und gespeichert werden. Das automatisierte Zellkultursystem PANsys3000 ist ein nahezu universell einsetzbares Werkzeug für die effiziente Zellkultur. In verschiedenen Testreihen konnte die Eignung des Systems für die Kultivierung einer Vielzahl von Zellen und Zelllinien nachgewiesen werden.

Features


Closed supply system with automated regulation of all necessary substances (CO2, O2, media, nutrients, temperature, activate materials and test substances).

Automated cell-culture system with which various cells, cell lines and media can be cultivated under controlled conditions.

Six separate cull culture chambers (multi-chamber system) with individual equipment of each chamber and supervision of all relevant cell-culture parameters.


Continuous analysis and documentation of all cell-culture parameters (temperature, CO2, O2, pH) with microscopic monitoring of the cell morphology and growth.

Life cell imaging: Continuous video-microscopic monitoring of the cells with complete storage, documentation and analysis. Morphological changes and growth behaviors can be quickly recorded and evaluated.


High-level microscopy system with phase contrast and multi-channel fluorescence microscope for detailed and complex microscopy and life-cell imaging applications. Flexible adaptation of the optical characteristics (filter, frequencies, etc.)

Saving and documentation of all relevant and recorded data of cell cultivation, including cell-culture parameters and microscopy data. Automated evaluation and analysis of all relevant culture parameters and microscopy images with powerful, modern software tools.


Applications

    • Stem-cell research
    • Development of serum-free media
    • Cloning and differentiation studies
    • Optimization of cell-culture media
    • Research of active substances
    • Research of cell-to-cell interactions
    • Drug development and substance screening
    • Tissue cultivation and tissue engineering
    • Cell-cycle investigations
    • Development of tissue-/organ-simulation
    • Cellular cytotoxicity tests to reduce animal testings
    • Endothelial flow-experiment with shear-stress
    • Simulation and optimization of production processes
    • Special customized customer applications

... and many more applications according to your needs !


Advantages


PANsys3000 offers you unique and extraordinary possibilities for in-vitro cultivation and research on the most diverse cell lines under in-vivo-like conditions.

PANsys3000 reduces the gap between in-vitro and in-vivo applications through a powerful cell-culture and life-cell imaging system with simple operability.

PANsys3000 enables the design of complex, artificial organ models, in order to research specific cell behavior and varied influencing factors, environmental conditions and active substances.

PANsys3000 improves the development quality through the significantly detailed analysis and documentation of all data related to cell culture, including the microscopy.

PANsys3000 reduces your development costs through automation and significant reduction of manual processes with significantly lower resource consumption.

PANsys3000 reduces your development times through the parallelization of the cell culture.

PANsys3000 offers reliable results along with significant reductions in development times and costs.


PANsys3000 Special Variants


PANsys3000
Expert Version
Expert-Version with brightfield and phasecontrast-microscope, fluidicpumps and incubation-chambers, including softwarepackage for systemcontrol and data- / image-analyzing
PANsys3000
Professional Version
Professional-Version with brightfield and phasecontrast-microscope, optimized fluidicpumps and special incubationchambers for flow-experiments, including softwarepackage for systemcontrol and data- / image-analyzing
PANsys3000
HighEnd Version
HighEnd-Version with brightfield-, phasencontrast- and 6-channel-fluorescence-microscope, sophisticated fluidicfeatures, several Incubationchambers, highend-softwarepackage for systemcontrol and data- / image-analyzing
Optional add-on Modules
O2-pH-Measuring Special measuring-unit for the detection of O2and pH in each cell-culture-chamber
Gas-Mixing-Module Special gas-mixing-module for the individual mixing of the incubationgas with O2-N2-CO2, suitable for special hypoxia- or hyperoxia-experiments
Cell Impedance Measuring Lab-on-a-chip to analyze impedance, O2, pH, ECAR and OCR in each cell-culture-chamber
Raman Spectroscopy Special Raman-spectroscopy-unit for the fast and non-invasive detection of cellular pathways and cellular differentiation, label-free with minimal cellular Interaction